Collects Symbiote Spider-Man 2099 #1-5. There's a new Symbiote on the loose in the year 2099! Set your time circuits ahead to the techno-dystopian future of 2099 - where local hero Miguel O'Hara, A.K.A. Spider-Man, is facing a hostile takeover…of his own body! Kron Stone, the Venom of 2099, wages an all-out assault on the Alchemax corporation, and the only hope of stopping him lies with the power awakened by a top-secret project gone terribly wrong. But what must Miguel sacrifice to seal the bond with his new Symbiote? His body? His mind? His very soul?! The battle between Spider-Man and Venom soon draws the attention of Loki - and as things quickly spiral out of control, the heroes (and villains) of 2099 must rally to try to protect Nueva York…and save Miguel from himself. But it may already be too late!
